Chiral donor–acceptor azetines as powerful reactants for synthesis of amino acid derivatives
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چکیده
منابع مشابه
Stereoselective synthesis of perillaldehyde-based chiral β-amino acid derivatives through conjugate addition of lithium amides
The Michael addition of dibenzylamine to (+)-tert-butyl perillate (3) and to (+)-tert-butyl phellandrate (6), derived from (S)-(-)-perillaldehyde (1), resulted in diastereomeric β-amino esters 7A-D in a moderately stereospecific reaction in a ratio of 76:17:6:1. After separation of the diastereoisomers, the major product, cis isomer 7A, was quantitatively isomerized to the minor component, tran...
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The Rh-TangPhos complex is an efficient hydrogenation catalyst for making chiral beta-amino acid derivatives. With the Rh-TangPhos system, high enantioselectivities (up to 99.6%) and turnover numbers have been obtained in the hydrogenation of E/Z isomeric mixtures of both beta-alkyl and beta-aryl beta-(acylamino)acrylates. [reaction: see text]
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چکیده ندارد.
CHIRAL SEPARATIONS Amino Acids and Derivatives See III /AMINO ACIDS AND DERIVATIVES: CHIRAL SEPARATIONS
use by the OPCW inspectorate. Use of GC with one or more spectrometric technique such as mass spectrometry is required to conRrm the presence of chemical warfare agents. For this reason many analyses are carried out by GC-MS under electron impact or chemical ionization conditions. For analyses involving low levels of chemical warfare agents in the presence of high levels of interfering chemical...
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3-Carboxy-1-sulfopyridin-1-ium chloride ([CPySO3H]+Cl-) as a novel ionic organocatalyst for thecondensation of aldehydes and 2-methylindole to synthesize bis(2-methyl-1H-indole) derivatives inacetonitrile at room temperature has been developed. Some tetrakis (2-methyl-1H-indole)derivatives have also been synthesized by the reaction of 2,2'-(butane-1,4-diylbis(oxy))dibenzaldehyde and 2-methylind...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2019
ISSN: 2041-1723
DOI: 10.1038/s41467-019-13326-8